When should statisticians become involved in a clinical trial?

1. When should statisticians become involved in a clinical trial? Why? (i.e., hint, watch Clinical Research Statistics for Non-Statisticians).

2. In your area of clinical practice what type of statistics have you seen used the most, predictive, causal or both (i.e., provide an example as part of your answer)? Why do you think this is?

1 reference each within 5 years peer reviewed article. Must be 100 words in length.

When should statisticians become involved in a clinical trial?
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